Cost and results of combined tirzepatide treatment for weight loss

A 5% reduction in body weight was achieved after four weeks of compounded tirzepatide therapy.

• The investigator's body mass index (BMI) decreased to 25.8 but did not meet the target of 25.
• Weight was regained within two weeks after stopping the therapy, reflecting a potential relapse similar to real-world outcomes.
• Side effects included bloating, increased thirst, and rapid intestinal emptying, which could be intolerable in a work setting.
• Weight-lifting strength was maintained, lap swimming speed remained stable, and endurance improved during the treatment period.
• Behavioral changes related to food cravings and exercise performance were observed but may be influenced by performance bias.

Simplified