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Tolerogenic probiotics and gut-brain axis: targeting pain receptors in neuroimmune disorders
Probiotics that reduce immune reactions and their effects on pain-related nerves in brain-immune disorders
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Abstract
Tolerogenic probiotics may offer therapeutic potential for neuroimmune disorders by affecting the gut-brain axis.
- These probiotics help promote immune tolerance and reduce inflammation in the body.
- They influence crucial cell types, including intestinal epithelial cells and enteroendocrine cells, which are important for gut health.
- Probiotics enhance the integrity of the gut barrier and regulate the secretion of hormones like GLP-1 and serotonin.
- They may help alleviate various types of pain by modulating key receptors involved in pain signaling.
- Challenges such as inconsistent dosing and limited clinical trials may hinder their effective use in clinical settings.
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