Frontiers in psychiatry

Using the addictive drug ketamine to treat addiction: revisiting the ketamine paradox

Updated

Abstract

Ketamine may provide a novel intervention for treatment-resistant depression and is being explored as an adjunctive treatment for addiction.

  • Substance use disorders and treatment-resistant depression pose significant global health challenges.
  • Existing treatments for these conditions often have high relapse rates and limited long-term effectiveness.
  • Ketamine is associated with rapid neuroplastic effects, which could be beneficial for these disorders.
  • Concerns about the potential for ketamine abuse remain a significant consideration in its use.

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Funding

Competing interests

No commercial or financial ties reported.
PubMed

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