Brain, behavior, & immunity - health

Ulinastatin may help prevent memory problems after surgery by changing gut bacteria and their fatty acids

Updated

Abstract

Evidence suggests that gut dysbiosis may be linked to postoperative cognitive dysfunction (POCD) following general anaesthesia.

  • Gut dysbiosis and dysfunction of the gut-brain axis are associated with POCD.
  • Ulinastatin has been noted for its anti-inflammatory and neuroprotective properties.
  • The impact of ulinastatin on the gut microbiome and related metabolites in the context of POCD is not yet understood.

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