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Abstract
Patients documented with persistent postsurgical pain exhibited systematic shifts in wake timing and heart rate circadian rhythms.
- Changes in wake timing and heart rate circadian rhythms were observed in patients with persistent postsurgical pain.
- Patients showed elevated amplitude and mesor in heart rate circadian rhythms.
- Wake timing was decoupled from heart rate circadian timing in those with persistent pain.
- These observed changes were not present in a comparison group without persistent pain documentation.
- The findings suggest a specific link between altered sleep patterns and persistent postsurgical pain.
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