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The beneficial effect of weight reduction on adverse cardiovascular outcomes following bariatric surgery is attenuated in patients with obstructive sleep apnea
Weight loss after bariatric surgery reduces heart risks less in people with sleep apnea
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Abstract
27 per cent of patients undergoing laparoscopic adjustable gastric banding (LAGB) had obstructive sleep apnea (OSA).
- Patients with OSA experienced a significantly higher percentage of cardiovascular events compared to those without OSA (35.6% vs 6.9%) at 3 years.
- Despite similar reductions in body mass index (BMI) of approximately 20%, the incidence of cardiovascular events was markedly different between the two groups.
- The cumulative rates of new onset stroke, heart failure, myocardial infarction, venous thrombosis, and pulmonary embolism remained higher in the OSA group even after matching for age, sex, BMI, and comorbidities.
- Patients with OSA who were treated with continuous positive airway pressure (CPAP) had lower cardiovascular event rates at 30 months compared to those who were not treated.
- OSA was identified as an independent predictor of cardiovascular events with a hazard ratio of 6.92.
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