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Abstract
The gut microbiota significantly influences brain development through various communication pathways.
- Gut microbes may affect brain development via neural, immune, endocrine, metabolic, and epigenetic pathways.
- Maternal microbiota and their metabolites may impact fetal brain development by crossing the feto-placental barrier.
- Temporal dynamics of gut colonization and brain maturation are important for understanding neurodevelopment.
- Microbial interactions are associated with neurodevelopmental disorders and could inform therapeutic strategies.
- Understanding the microbiota-gut-brain axis may lead to early-life interventions for optimizing neurodevelopment.
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