Evaluation of the relationship between xanthine oxidase activity and metabolic syndrome in a population group in Bangladesh.

Sep 2, 2024Scientific reports

Link between xanthine oxidase activity and metabolic syndrome in people from Bangladesh

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Abstract

Serum (XO) activity was significantly higher in females (6.17 ± 3.77 U/L) compared to males (4.00 ± 2.77 U/L) (p < 0.001).

  • Participants with (MetS) had significantly higher mean serum XO levels (5.34 ± 3.39 U/L) than those without MetS (3.86 ± 2.90 U/L) (p < 0.001).
  • The prevalence of MetS and its components, such as blood pressure and blood glucose, increased across the XO quartiles (p < 0.001).
  • Regression analysis indicated that XO activity was significantly and independently associated with the prevalence of MetS (at least p < 0.05 for all cases).
  • XO activity was also associated with components of MetS, including elevated blood pressure, high blood glucose, and low HDL cholesterol (at least p < 0.05 for all cases).
  • Findings suggest that serum XO may serve as a useful marker of MetS.

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Key numbers

6.17 ± 3.77 U/L
Higher Serum Activity in Females
Serum activity in females vs. males
5.34 ± 3.39 U/L
Serum Levels in vs. Non-
Mean serum levels in participants with vs. without
p < 0.05
Independent Association with
Statistical significance of activity association with

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