Comparing two sedation guides during short-term breathing machine use

Patients in the BIS guided group received higher doses of midazolam and propofol compared to the SAS guided group.

• The total time under sedative control was significantly longer in the BIS guided group compared to the SAS group.
• Wake-up time was shorter for patients in the BIS guided group.
• No significant differences were found in APACHE II scores, duration of mechanical ventilation, or sedation time between the two groups.
• The incidence of adverse events, including restlessness, endotracheal tube resistance, and delirium, did not significantly differ between the two groups.

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