Diabetes, obesity & metabolism

Immediate Effects of Acarbose and Canagliflozin, Alone and Together, on Blood Sugar and Gut Hormone After Meals in People with Low Blood Sugar After Weight Surgery

Updated

Abstract

The acute effects of acarbose and canagliflozin on postprandial total GLP-1 and glycaemic responses were evaluated in adults with post-bariatric hypoglycaemia.

  • Acarbose and canagliflozin may influence total GLP-1 levels after meals.
  • The combination of acarbose and canagliflozin could affect glycaemic responses during a mixed meal test.
  • Post-bariatric hypoglycaemia may alter the effectiveness of these medications.

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