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Abstract
High-dose semaglutide may induce immunological remodeling of adipose and hepatic tissues during weight cycling.
- Weight loss is known to improve metabolic dysfunction linked to obesity.
- Resolution of inflammation in fat tissue may not fully occur and can return when weight is regained.
- The effects of high-dose semaglutide on immune changes in fat and liver tissue during weight fluctuations are not yet established.
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