Adipose Tissue Circadian Clocks: Implications for Metabolism and Metabolic Dysfunction

Dec 12, 2025Obesity reviews : an official journal of the International Association for the Study of Obesity

Body fat's internal clocks may affect metabolism and metabolic problems.

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Abstract

Circadian rhythms in adipose tissue may influence metabolic and cardiovascular health.

  • Adipose tissue acts as an endocrine organ, releasing signaling molecules that affect the body.
  • The circadian clock regulates various physiological functions based on environmental cues.
  • Recent studies show that certain genes in adipose tissue follow circadian expression patterns.
  • Disruptions in circadian rhythms could lead to problems with adipose tissue and metabolism.
  • Understanding these circadian mechanisms may help develop strategies to reduce metabolic and cardiovascular disease risk.
  • This review discusses the connection between circadian rhythms and adipose tissue metabolism, and potential therapies targeting this relationship.

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