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Abstract
Aging is linked to various biological processes that may contribute to Parkinson's Disease (PD).
- Aging-related oxidative stress and mitochondrial dysfunction are associated with dopaminergic neuronal death.
- Persistent activation of glial cells and dysregulation of cellular repair mechanisms are observed with aging.
- Systemic changes, such as metabolic imbalance and gut microbiota dysbiosis, may influence PD development through the gut-brain axis.
- Therapies like antioxidants and stem cell treatment show potential for managing PD.
- Lifestyle changes, including diet and exercise, may help delay or prevent the onset of PD.
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