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Anterior ischemic optic neuropathy in patients treated with semaglutide: report of four cases with a possible association
Sudden vision nerve damage possibly linked to semaglutide treatment: report of four cases
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Abstract
Four male patients developed (NAION) during treatment with semaglutide, with three cases having treatment durations of less than one year.
- All patients exhibited significant optic disc swelling and fluid in the retina as seen on imaging.
- Three patients had small openings in Bruch's membrane, measuring less than 1.4 mm.
- One patient showed optic disc drusen, a condition often linked with visual impairment.
- Visual field defects were related to loss of ganglion cells, indicating potential damage to the optic nerve.
- Systemic risk factors varied among patients; two were only obese.
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Key numbers
3 of 4
Diameter < 1.4 mm
measurements in affected patients
18 kg
Weight Loss
Weight loss achieved by Case 1 after 11 months on semaglutide