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Abstract
Four male patients developed (NAION) during treatment with semaglutide, with three cases having treatment durations of less than one year.
- All patients exhibited significant optic disc swelling and fluid in the retina as seen on imaging.
- Three patients had small openings in Bruch's membrane, measuring less than 1.4 mm.
- One patient showed optic disc drusen, a condition often linked with visual impairment.
- Visual field defects were related to loss of ganglion cells, indicating potential damage to the optic nerve.
- Systemic risk factors varied among patients; two were only obese.
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