[Review of antidepressants from the TCAs to the third generation drugs].
Overview of antidepressant drugs from early tricyclics to newer third-generation treatments
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Abstract
The review discusses various antidepressants, including selective serotonin reuptake inhibitors (SSRIs) and their pharmacodynamic properties.
- Unipolar major depressive disorder (MDD) has multiple potential pathomechanisms.
- Antidepressants range from older tri- and teracyclic drugs to modern dual-acting options.
- Pharmacodynamic properties of each antidepressant subgroup highlight their therapeutic benefits and occasional side effects.
- Combinations of antidepressants may offer benefits but also come with potential disadvantages.
- An objective approach is suggested to aid psychiatrists in selecting optimal treatment methods.
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