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Abstract
Advances in understanding Mycobacterium tuberculosis may aid in the development of new anti-tuberculous drugs.
- Critical information on the entire genome of Mycobacterium tuberculosis has been elucidated.
- Knowledge of various mycobacterial virulence genes may enhance the identification of new drug targets.
- Potential pharmacological targets for future anti-tuberculous drug development include specific genes related to MTB.
- Promising new anti-tuberculous agents under development include nitroimidazoles, diarylquinolines, and oxazolidinones.
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