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Arg-vasopressin content in the suprachiasmatic nucleus of rat pups: circadian rhythm and its development
Daily cycle and development of arg-vasopressin levels in the brain's body clock area of young rats
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Abstract
AVP levels in the rat pup suprachiasmatic nucleus increased from postnatal day 1, reaching adult levels by postnatal days 10-12.
- AVP content demonstrates a marked increase over the early postnatal period.
- A diurnal rhythm similar to that of adults appears at postnatal days 10-12 under light-dark cycle conditions.
- The peak AVP levels are observed during the early light period, while the lowest levels occur at the end of the light period.
- Circadian rhythms of AVP persist for 7 days under constant dark or constant light conditions.
- Oscillation of AVP levels begins after postnatal day 10-12, indicating a developing rhythmicity during the nursing phase.
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