EBioMedicine

Links between air pollution, green space, and death rates in people with diabetes over 11 years

Circadian Biology Weekly Brief ↗PubMed ↗DOI ↗

Updated

Abstract

During a median follow-up of 7.9 years, 22,205 deaths were recorded among 174,063 individuals with type 2 diabetes mellitus.

  • Higher exposure to fine particulate matter (PM) was significantly associated with increased risks for all mortality outcomes.
  • The strongest links between PM exposure and mortality were found for diabetes-related peripheral vascular diseases (hazard ratio: 2.70) and gastrointestinal cancer (hazard ratio: 2.44).
  • Nitrogen dioxide (NO) exposure became significantly associated with mortality at concentrations above approximately 45 μg/m³, particularly for lung cancer (hazard ratio: 1.20) and gastrointestinal cancer (hazard ratio: 1.19).
  • Each interquartile range increase in green space exposure (measured by NDVI) was linked to reduced mortality risks, with hazard ratios ranging from 0.76 to 1.00.
  • The relationship between greenness and mortality was partly mediated by reductions in PM (23.80%) and NO (26.60%).
  • A significant negative interaction was observed between NO and greenness, while no interaction was found between PM and greenness.

Simplified

Full Text

We can’t show the full text here under this license.
View Full Text ↗

Funding

Competing interests

Declaration of interests All authors declared no potential conflicts of interest.
PubMed

Related papers

Sep '22
Long-Term Exposure to Low Levels of Air Pollutants and Its Links to Death and Illness in European Groups
cited by 90 papers
meta-analysis
Oct '22
Links Between Air Pollution and Death Rates in Areas with Low Pollution: Phase 2
research support, u.s. gov't, non-p.h.s.
May '22
Nearby greenery, air pollution, and new cases of blocked heart arteries in China
top 5% journal
cited by 21 papers
journal article
Sep '22
Air pollution, green spaces, and overweight risk in middle-aged and older adults in China
top 10% journal
cited by 19 papers
research support, non-u.s. gov't
Oct '22
Green spaces reduce the link between long-term air pollution and high blood pressure in Northern China
top 20% journal
cited by 17 papers
research support, non-u.s. gov't
Jan '22
Long-term exposure to low levels of air pollution and death rates in 28 million people across seven large European studies
top 1% journal
cited by 317 papers
meta-analysis

What Lands in Your Inbox Each Week:

  • 📚7 fresh studies
  • 📝plain-language summaries
  • ✅direct links to original studies
  • 🏅top journal indicators
  • 📅weekly delivery
  • 🧘‍♂️always free

Recent issues from the circadian biology brief

issue #49
Your body clock controls which drugs work — and a protein called gp78 is why
6 days ago7 studies
issue #48
A blood test can now estimate your internal clock time using just 60 proteins
1 week ago7 studies
issue #47
Your body clock controls liver fibrosis — and scientists just found the on/off switch
2 weeks ago7 studies
issue #46
Night shift workers' metabolomes fall out of sync — and glucose pays the price
3 weeks ago7 studies
issue #45
80% of FDA-approved drug targets show clock-dependent activity — timing may be everything
4 weeks ago7 studies
issue #44
Sleeping late on weekends is independently linked to higher cardiovascular disease risk
5 weeks ago7 studies
issue #43
A smartphone app cut mood episode recurrence 3.4x in people with depression and bipolar disorder
6 weeks ago7 studies
issue #42
Morning cancer immunotherapy linked to 49% vs 40% disease control rate in 969 patients
7 weeks ago7 studies
issue #41
Timing cancer treatment before 3pm nearly doubled survival in lung cancer patients
8 weeks ago7 studies
issue #40
Male mice lived 12% longer when they ate only during an 8-hour window at night
9 weeks ago7 studies
explore the archive
See more issues from the circadian biology brief