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Astilbin ameliorates intracerebral hemorrhage-induced secondary brain injury by upregulating Treg cells in mice
Astilbin reduces brain damage after bleeding by increasing protective immune cells in mice
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Abstract
Astilbin may improve neurofunctional impairments following intracerebral hemorrhage (ICH) in mice.
- Astilbin reduces iron buildup and neuronal death in brain tissue affected by ICH.
- It decreases cerebral swelling and lessens damage to the blood-brain barrier associated with ICH.
- The flavonoid increases the secretion of specific anti-inflammatory factors after ICH.
- Astilbin promotes the accumulation of regulatory T cells in the brain near the hematoma.
- These effects could contribute to better outcomes following ICH.
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