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Abstract
Dysfunction of the autophagy-lysosomal pathway is believed to be the main factor leading to the accumulation of amyloid-β and tau proteins, which are associated with Alzheimer's disease.
- The autophagy-lysosomal pathway plays a critical role in removing harmful substances within cells.
- Disruption of lysosomal function is linked to metabolic disorders and the pathogenesis of Alzheimer's disease and other tau-related diseases.
- Damage to autophagy is associated with neurodevelopmental abnormalities and neurodegenerative diseases.
- The relationship between autophagy and oligodendrocytes may offer new perspectives for understanding neurodegenerative diseases.
- Enhancing autophagy function could provide potential treatment strategies for alleviating conditions in Alzheimer's disease patients.
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