Frontiers in cardiovascular medicineJul 29, 2026

Reduced blood pressure reflex in Long-COVID patients as a way to identify different types of nervous system problems

Long Covid Weekly Brief ↗PubMed ↗DOI ↗OA ↗

Updated Aug 3, 2026

Abstract

Long-COVID is associated with cardiovascular alterations, including Postural Orthostatic Tachycardia Syndrome (POTS) and decreased baroreceptor sensitivity.

Long-COVID describes a range of COVID-19 side effects lasting over three months.
Higher rates of POTS and reduced baroreceptor sensitivity have been reported in Long-COVID patients.
Many Long-COVID patients show symptoms of orthostatic intolerance that do not fully meet established POTS criteria.
The study aims to evaluate whether decreased baroreceptor sensitivity can help in diagnosing varying degrees of autonomic dysfunction.

Simplified

Long-COVID describes a variety of COVID-19 side effects lasting longer than three months. Among these side effects are cardiovascular alterations, such as Postural Orthostatic Tachycardia Syndrome (POTS), caused by an autonomic nervous system dysfunction. A higher incidence of POTS and decreased baroreceptor sensitivity (BRS) has been reported in Long-COVID patients. Many of these patients present orthostatic intolerance similar to that observed in POTS, which does not strictly coincide with the criteria that have previously been established for POTS subtypes. Therefore, we aim to determine if the decrease of the baroreceptor sensitivity is enough to diagnose different degrees of the autonomic dysfunction spectrum.

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Funding

Competing interests

No commercial or financial ties reported.

PubMed

Reduced blood pressure reflex in Long-COVID patients as a way to identify different types of nervous system problems

Abstract

Full Text

Funding

Competing interests

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