Benzofuran derivatives and their anti-tubercular, anti-bacterial activities

Benzofuran derivatives show excellent in vitro and in vivo activity against drug-sensitive and drug-resistant pathogens.

• Benzofuran is a key structural component in many biologically active natural products.
• Certain benzofuran derivatives exhibit unique mechanisms of action against tuberculosis and bacterial infections.
• Several benzofuran derivatives are already in clinical use for treating various diseases.
• Recent advances highlight the potential of benzofuran derivatives as new anti-tubercular and anti-bacterial agents.
• The relationship between the chemical structure of benzofuran derivatives and their biological activity is discussed to inform future drug development.

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