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Abstract
Long COVID is associated with prolonged neurological symptoms, including cognitive impairment and sleep disturbances.
- Symptoms of Long COVID may arise from ongoing neuroinflammation linked to a viral reservoir.
- Activation of other viruses and prolonged inflammatory responses could contribute to symptom persistence.
- The viral Spike protein may stimulate proinflammatory signaling through specific receptors in the brain.
- Bezisterim (NE3107), an anti-inflammatory compound, may inhibit neuroinflammation driven by these processes.
- This compound is being developed for conditions where similar inflammation is involved in cognitive decline.
Simplified
Long Covid