Bilateral projections to the thalamus from individual neurons in the inferior colliculus

Dec 12, 2018The Journal of comparative neurology

Individual hearing-related neurons sending signals to both sides of the brain's relay center

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Abstract

Up to 37% of cells projecting to the ipsilateral medial geniculate body originate from the inferior colliculus and project bilaterally.

  • Cells in the inferior colliculus that project bilaterally to the medial geniculate body were identified using fluorescent retrograde tracers.
  • Bilaterally projecting cells comprised up to 37% of the population sending projections to the ipsilateral medial geniculate body.
  • These cells constituted up to 73% of those projecting to the contralateral medial geniculate body.
  • Approximately 20% of the bilaterally projecting cells were identified as GABAergic, while the majority were glutamatergic.
  • The bilaterally projecting cells originate from all major subdivisions of the inferior colliculus.
  • This population of cells may serve different functions compared to the larger unilateral projections.

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Full Text

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