Annual review of nutrition

Bile Acids as Controllers of Metabolism and Nutrient Detection

Updated

Abstract

Bile acids are important for nutrient absorption and may influence metabolic health.

  • Bile acids are natural compounds that help absorb nutrients and regulate metabolism.
  • The brain-gut-liver axis is crucial for maintaining glucose, bile acid, and immune balance.
  • Changes in fasting and feeding can alter the composition and quantity of bile acids in the gut.
  • Bile acid signaling is linked to how the body uses fats and sugars and may help reduce inflammation.
  • Problems with bile acid metabolism, due to factors like diet or genetic mutations, could lead to diseases such as diabetes and obesity.
  • Bile acids and their derivatives have potential as treatments for inflammatory metabolic diseases.

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