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Working against the biological clock: a review for the Occupational Physician
Health challenges of working against the body’s natural daily rhythms
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Abstract
Disruption of the biological clock in night shift workers is associated with adverse health effects.
- The biological clock, located in the suprachiasmatic nucleus, synchronizes molecular biological clocks in peripheral tissues.
- Circadian rhythms in humans are primarily influenced by the light-dark cycle.
- Alterations in sleep-wake patterns from night shifts may lead to biological clock disruptions.
- Health risks linked to circadian rhythm perturbation include various clinical symptoms.
- Occupational screening for these symptoms in shift workers is recommended to identify health risks.
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