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Blood Clock Correlation Distance as a new marker to detect daily rhythm disruptions in cancer survivors with insomnia
Updated
Abstract
Essence
was linked to circadian disruption and insomnia severity in cancer survivors with insomnia.
Evidence
This biomarker analysis used blood RNA-sequencing from cancer survivors with insomnia in the YOCAS-II trial and compared BloodCCD scores with healthy individuals and insomnia severity patterns across intervention arms.
Caveat
The findings are correlational, and the abstract does not report sample size, effect sizes, or whether BloodCCD changed with yoga, CBT-I, or placebo treatment.
Simplified
Key numbers
9
Score Increase
scores for severe insomnia patients
8.24
Score Comparison
scores for moderate insomnia patients
7.94
Score for Subthreshold Insomnia
scores for subthreshold insomnia patients