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Brain GLP‐1 and the regulation of food intake: GLP‐1 action in the brain and its implications for GLP‐1 receptor agonists in obesity treatment
Brain GLP-1's role in controlling food intake and its importance for obesity treatments using GLP-1 receptor drugs
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Abstract
This review examines the regulatory roles of gut-derived and neuronally produced glucagon-like peptide 1 (GLP-1) in physiological systems.
- Peripheral and central sources of GLP-1 may represent separate or interconnected systems.
- The structure of the brain GLP-1 system could vary, consisting of distinct sections or acting as a unified system.
- Understanding these relationships may inform the effectiveness of GLP-1 receptor agonists in anti-obesity treatments.
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