Trials of bright light exposure and melatonin administration in a patient with non‐24 hour sleep‐wake syndrome

Jun 17, 1998Psychiatry and clinical neurosciences

Effects of bright light and melatonin treatment in a person with a non-24-hour sleep-wake cycle

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Abstract

A patient with non-24 h sleep-wake syndrome achieved appropriate entrainment to a 24 h day through bright light exposure and melatonin treatment.

  • Morning bright light exposure and evening melatonin both phase-advanced the patient's sleep-wake cycles.
  • These treatments were associated with a phase-advanced melatonin rhythm.
  • The patient struggled to maintain morning bright light therapy after discharge.
  • Melatonin treatment was found to be better tolerated due to its ease of application.

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