Nature neuroscience

How Bright Light Reduces Eating and Weight Gain

Updated

Abstract

Essence

Bright light reduced feeding and weight gain in mice through a retina-vLGN-LHA visual circuit.

Evidence

Mouse neural-circuit experiments mapped SMI-32-expressing ON-type retinal ganglion cells to vLGN GABAergic neurons and LHA GABAergic neurons, with pathway activation suppressing food intake and weight gain.

Caveat

The findings are limited to mice and circuit-level manipulations, so they do not show that bright light therapy produces comparable weight effects in humans.

Simplified

Full Text

Full text is available at the source.

Funding

Competing interests

0 of 17
authors report competing interests
17 report none
PubMed

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