American heart journal

Design and starting details of the CagriSema heart health outcomes trial (REDEFINE 3)

Updated

Abstract

Cagrilintide-semaglutide (CagriSema) may contribute to significant weight reduction and improved glycemic control.

  • CagriSema is a combination treatment that includes an amylin receptor agonist and a glucagon-like peptide-1 receptor agonist.
  • It is administered subcutaneously once weekly.
  • Participants with excess body fat and type 2 diabetes experienced notable weight loss.
  • The treatment is associated with enhanced control of blood sugar levels.

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