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CATP is a critical component of the Neurospora circadian clock by regulating the nucleosome occupancy rhythm at the frequency locus
CATP helps control the daily rhythm in Neurospora by managing DNA packaging at the clock gene
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Abstract
A circadian histone occupancy rhythm at the frq promoter is regulated by FREQUENCY (FRQ).
- Histone occupancy at the frq promoter exhibits a rhythmic pattern that is essential for clock function.
- Clock ATPase (CATP) has been identified as a crucial component of the circadian clock.
- CATP is shown to associate with the frq locus and other target genes of the clock.
- The role of CATP includes promoting the removal of histones at these gene loci.
- This histone removal facilitates the transcription of circadian genes, indicating its importance in clock regulation.
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