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Long-term stress hormone changes behavior in conflict situations and stops ketamine from reducing conflict in mice
Updated
Abstract
Three weeks of corticosterone exposure increased conflict levels in mice without inducing anhedonia.
- Chronic corticosterone exposure selectively prolonged action initiation in conflict scenarios.
- Ketamine reduced conflict behavior in control mice but failed to do so in corticosterone-treated mice.
- Stress may disrupt ketamine's ability to influence conflict-related behavior.
- Findings indicate that chronic stress alters decision-making processes related to reward and danger.
Simplified
Psychedelic Science