EBioMedicine

Using timing of treatments to improve care in glioblastoma: current knowledge and future possibilities

Circadian Biology Weekly Brief ↗PubMed ↗DOI ↗

Updated

Abstract

Chronotherapy may optimize treatment timing for glioblastoma multiforme (GBM) to enhance efficacy and reduce side effects.

  • Circadian rhythms influence drug metabolism and treatment outcomes in cancer.
  • Chronotherapy has been explored for various cancers, showing mixed results.
  • Glioblastoma multiforme (GBM) is the most aggressive brain tumor with poor prognosis.
  • Recent advances in chronotherapy could improve the effectiveness of existing treatments like radiotherapy and temozolomide.
  • Novel treatments targeting the circadian clock may offer new therapeutic options for GBM.

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Funding

Competing interests

Declaration of interests The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
PubMed

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