Circadian clock synchrony and chronotherapy opportunities in cancer treatment

Aug 7, 2021Seminars in cell & developmental biology

Body Clock Alignment and Timing-Based Treatment Options for Cancer

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Abstract

Circadian rhythms in gene expression and cellular processes have been observed throughout the human body.

  • Disruption of daily rhythms by factors such as light exposure, food intake, or genetic mutation may be linked to cancer development.
  • Some medications may be more effective at certain times of day.
  • There is a limited number of clinical studies focusing on daily rhythms in patient or drug timing as treatment strategies.
  • Recent evidence suggests that daily rhythms and their regulation in tumors could inform personalized medicine approaches for cancer patients.

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