BioEssays : news and reviews in molecular, cellular and developmental biology

The body’s daily rhythm system in the mammal’s retina

Updated

Abstract

The master pacemaker controlling 24-hour rhythms in mammals is found in the suprachiasmatic nuclei of the hypothalamus.

  • Circadian rhythms are generated internally by organisms rather than solely responding to environmental changes.
  • The circadian clock influences diverse functions including sleep, food intake, body temperature, heart rate, and hormone release.
  • The retinal circadian clock is identified as the first extra-SCN circadian oscillator in mammals.
  • Physiological, cellular, and molecular rhythms in the retina are believed to be regulated by a network of circadian clocks.

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