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Disrupted daily rhythms in ICU patients: pathways, gene activity, and treatments
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Abstract
Intensive care unit patients often experience poor quality daytime sleep and fragmented nocturnal sleep.
- Patients typically show pathologic wakefulness and a lack of slow wave sleep and rapid eye movement.
- Circadian desynchronization may occur in critically ill patients, influenced by various contributing factors.
- Observed circadian abnormalities could impact their overall sleep patterns.
- Understanding these circadian rhythms may inform future therapeutic approaches in critical care.
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