Disrupted body clocks may reduce liver protein production during long-term light cycle changes, with differences by sex and improvement from timing treatments

Declarations. Ethics approval and consent to participate: All animal procedures were conducted in accordance with the European Union Directive 2010/63/EU on the protection of animals used for scientific purposes and the Russian Federation Ministry of Health guidelines for the care and use of laboratory animals. The study protocol was approved by the Institutional Animal Care and Use Committee of the Avtsyn Research Institute of Human Morphology, Petrovsky National Research Centre of Surgery (Moscow, Russia; Approval No. 12/24 dated March 10, 2024). All efforts were made to minimize animal suffering and to reduce the number of animals used. Informed consent is not applicable to this study as it did not involve human participants. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.