Circadian expression of clock genes in mouse macrophages, dendritic cells, and B cells

Oct 25, 2011Brain, behavior, and immunity

Daily patterns of clock gene activity in mouse immune cells

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Abstract

Functional molecular clock mechanisms exist in splenic macrophages, dendritic cells, and B cells.

  • Circadian rhythms influence various physiological processes in mammals.
  • Gene expression of clock genes and transcription factors was measured in immune cells.
  • Splenic macrophages, dendritic cells, and B cells show circadian changes in gene expression.
  • The study involved mice under both a light-dark cycle and constant environmental conditions.

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