Current perspective on circadian function of the kidney

Dec 22, 2023American journal of physiology. Renal physiology

Current understanding of the kidney’s daily rhythms

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Abstract

Circadian rhythms may significantly influence kidney function and health.

  • Misalignment with natural light-dark cycles, such as due to shift work or irregular eating, could lead to adverse health effects.
  • Cell-autonomous molecular clocks are involved in regulating circadian physiology within the kidney.
  • Current knowledge of the mechanisms controlling circadian function in the kidney is limited and still developing.
  • Meal timing may play a critical role in influencing circadian rhythms and associated kidney functions.
  • Understanding circadian control in the kidney may uncover insights into disorders like hypertension, obesity, and chronic kidney disease.

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