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Meal frequency patterns determine the phase of mouse peripheral circadian clocks
Meal timing shapes the daily rhythms of body clocks in mice
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Abstract
The phase of was altered by the amount of food and the interval between feeding time points.
- Irregular eating patterns influence the synchronization of peripheral circadian clocks in mammals.
- The amount of food consumed and the timing of meals affect how these clocks adjust.
- Feeding frequency does not impact peripheral clock phases if the intervals between meals remain consistent.
- Separating a late dinner into two half-dinners may help mitigate disruptions in clock synchronization.
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Key numbers
20%
Phase Advance with Calorie Restriction
Mice experienced a phase advance in peripheral tissues under 20% calorie restriction compared to free-feeding.