“Circadian misalignment and the gut microbiome. A bidirectional relationship triggering inflammation and metabolic disorders”- a literature review

Emerging studies have linked gut dysbiosis to sleep disorders and circadian rhythm misalignment.

• Intermittent hypoxia from obstructive sleep apnea has been shown to alter the gut microbiome.
• Circadian rhythm disorders, such as shift work disorders, may be influenced by gut dysbiosis.
• Both central and peripheral biological clocks can interact with gut microbiota and their byproducts.
• Metabolic pathways involved in processing carbohydrates, proteins, and lipids may be connected to changes in the gut microbiome.
• There are currently no studies examining the effects of gut dysbiosis on delayed sleep phase and advanced sleep phase syndromes.

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