Daily rhythms in immune system activity

The immune system is directly controlled by circadian rhythms, which may influence its response to infections.

• The circadian system synchronizes organ systems to environmental changes.
• Molecular clocks within immune cells are influenced by systemic circadian cues.
• The suprachiasmatic nucleus (SCN) serves as the master circadian pacemaker, sending timing information to the immune system.
• Daily variations in immune function are governed by signals from the SCN.
• Circadian disruption can lead to a lack of coordination in immune responses and increased vulnerability to diseases.

Simplified