Indication of circadian oscillations in the rat pancreas

Apr 20, 2004FEBS letters

Signs of daily biological rhythms in the rat pancreas

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Abstract

Robust circadian expression of clock genes was observed in the pancreatic tissue of rats.

  • The major clock genes Per1 and Bmal1 exhibited clear daily patterns of expression.
  • The presence of a potential peripheral oscillator in the pancreas is suggested.
  • The specific regulatory role of this pancreatic oscillator on islet functions is not yet clear.

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