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Abstract
Circadian rhythms in bile acid synthesis and transport are crucial for liver function and metabolism.
- The circadian clock regulates physiological and behavioral processes in living organisms.
- Bile acids are important signaling molecules that influence glucose, lipid, energy, and medication metabolism.
- Bile acid synthesis and the activity of enzymes and receptors involved in bile acid regulation show distinct daily variations.
- Disruption of circadian rhythms can lead to imbalances in bile acid homeostasis.
- Circadian clock disruption, along with restricted feeding and sleep disturbances, is associated with cholestatic and metabolic diseases.
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