How daily body clocks relate to depression in people

Depression is associated with high incidence, high disability, and high recurrence rates.

• Circadian rhythms regulate various physiological and behavioral processes in humans.
• Previous studies indicate a close connection between circadian rhythmicity and depression.
• Factors such as shift work, jet lag, and light exposure at night may influence the development of depression.
• Non-pharmacological interventions based on circadian rhythm regulation have shown clinical value in improving depression.
• Future research may explore wearable devices and diverse intervention methods to better understand neural mechanisms related to depression.

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