Circadian rhythms, gut microbiota, and diet: Possible implications for health

May 28, 2023Nutrition, metabolism, and cardiovascular diseases : NMCD

How Body Clocks, Gut Bacteria, and Diet May Affect Health

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Abstract

A desynchronization of circadian rhythms is closely associated with alterations in gut microbiota composition and function.

  • More than half of the gut microbiota composition fluctuates rhythmically throughout the day.
  • Circadian rhythms may influence gut microbiota, which in turn could affect the host's biological clock.
  • Alterations in gut microbiota due to circadian desynchronization are linked to increased risk of various health issues, including cardiovascular disease, cancer, irritable bowel disease, and depression.
  • Meal timing and diet quality appear to play a key role in maintaining the balance between circadian rhythms and gut microbiota.
  • Short-chain fatty acids produced by gut microbiota may be significant in this relationship.

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