Disruption of Circadian Rhythms and Sleep on Critical Illness and the Impact on Cardiovascular Events

Jul 7, 2015Current pharmaceutical design

How Disturbed Sleep and Body Clocks in Serious Illness May Affect Heart Problems

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Abstract

Disturbed circadian rhythms may have a profound adverse impact on cardiovascular health.

  • The cardiovascular system exhibits significant daily rhythms in heart rate, blood pressure, and cardiac function.
  • Circadian rhythms are important for coordinating physiological processes that maintain cardiovascular health.
  • Disturbances in circadian rhythms and sleep could negatively affect recovery from heart attacks and lead to heart disease.
  • Sleep disorders, such as obstructive sleep apnea, are associated with detrimental effects on cardiovascular health.
  • Altered nocturnal blood pressure profiles may contribute to cardiovascular pathophysiology.

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Full Text

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