The circadian syndrome predicts cardiovascular disease better than metabolic syndrome in Chinese adults

The prevalence of circadian syndrome (CircS) among Chinese adults aged ≥40 years is 39.0%.

• CircS and metabolic syndrome (MetS) are both directly associated with prevalent cardiovascular disease (CVD).
• The odds ratio for prevalent CVD is higher for CircS than for MetS in both men and women.
• The five-year incidence of CVD is 15.1% for CircS and 14.0% for MetS.
• CircS components provide better predictive power for both prevalent and incident CVD than MetS components.
• Area under the ROC (AUC) values indicate higher predictive accuracy for CircS compared to MetS in both genders.

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