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Clinical Outcomes and Safety of Upper Endoscopy While on Glucagon-Like Peptide-1 Receptor Agonists
Safety and results of upper endoscopy in people taking GLP-1 receptor agonist medications
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Abstract
GLP-1 receptor agonists may delay gastric emptying and could lead to retained gastric contents during esophagogastroduodenoscopy.
- Concerns arise regarding the safety of using GLP-1 receptor agonists during elective procedures due to their effect on gastric emptying.
- The American Society of Anesthesiologists recommends holding GLP-1RAs for 1 dosing cycle before elective procedures.
- In contrast, the American Gastroenterological Association suggests that asymptomatic patients may proceed with endoscopy without withholding medication.
- Recommendations vary due to insufficient outcomes data on GLP-1 receptor agonists related to endoscopic procedures.
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